Activity record

PGDB_A078392

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

Dmax = 83 %

TargetKRAS
Time18 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001227
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031955
Compound IDPGDB_C031955
CompoundI-15
Source record IDPGDB_C031955
InChIKeyZJVJHHJRNMBREP-WTGCYTDFSA-N

Assay context

Assay IDPGDB_AS001227
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-15

I-15 enlarged structureI-15 location on patent page 249
Activity table
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