Activity record

PGDB_A078478

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 5.8 nM

E3 ligaseCRBN
Cell lineSK-CO-1
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS002392
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031992
Compound IDPGDB_C031992
CompoundI-53;I-53
Source record IDPGDB_C031992
InChIKeyLVHQLVVMGWLAJL-INGXIVQOSA-N

Assay context

Assay IDPGDB_AS002392
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineSK-CO-1
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-53;I-53

I-53;I-53 enlarged structureI-53;I-53 location on patent page 284
Activity table
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