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SIMM · NJU
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·
SIMM · NJU
Activity record
PGDB_A078559
Assay: % Degradation
Target: GSPT1
QC: ambiguous
Activity overview
DC50 > 3000 nM
Target
GSPT1
E3 ligase
CRBN
Cell line
HEK293
Time
18 h
Assay / Readout
luminescence / DC50
Assay ID
PGDB_AS001690
Patent
WO2026114958A1
QC status
ambiguous
Evidence details
Compound, assay context, and source
Compound
Compound ID
PGDB_C031955
Compound
I-15
Source record ID
PGDB_C031955
InChIKey
ZJVJHHJRNMBREP-WTGCYTDFSA-N
Assay context
Assay ID
PGDB_AS001690
Assay family
% Degradation
Assay system
cell_based
Readout
DC50
Technology
luminescence
Treatment time
18 h
Target
GSPT1
E3
CRBN
Cell line
HEK293
Organism
Homo sapiens
Source evidence
Patent ID
WO2026114958A1
Compound location
I-15
Activity table