Activity record

PGDB_A078948

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 = 36.6 nM

TargetVAV1
Time24 h
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS001571
PatentWO2026098637A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031198
Compound IDPGDB_C031198
Compound4-2
Source record IDPGDB_C031198
InChIKeyRIFDPWJLHNZGEX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001571
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
Treatment time24 h
TargetVAV1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026098637A1
Compound location

4-2

4-2 enlarged structure4-2 location on patent page 100
Activity table
Page 100 · table single