Activity record

PGDB_A079081

Assay: % DegradationTarget: KRASQC: standardized
Activity overview

DC50 = 10 nM

TargetKRAS
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002526
PatentWO2026114958A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031945
Compound IDPGDB_C031945
CompoundI-5;I-5
Source record IDPGDB_C031945
InChIKeyBWJNHTJXISPWHZ-BRIYLYBJSA-N

Assay context

Assay IDPGDB_AS002526
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-5;I-5

I-5;I-5 enlarged structureI-5;I-5 location on patent page 247
Activity table
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