Activity record

PGDB_A079380

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 90-100 %

TargetCRBN
E3 ligaseCRBN
Concentration2 uM
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS001031
PatentWO2026061475A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C030361
Compound IDPGDB_C030361
CompoundGT-10186
Source record IDPGDB_C030361
InChIKeyFXWSWTPGESFYJA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001031
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration2 uM
Detection targetcell_inhibition
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2026061475A1
Compound location

GT-10186

GT-10186 enlarged structureGT-10186 location on patent page 69
Activity table
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