Assay

PGDB_AS001031

System: cell_basedTarget: CRBN
Assay context summary

Assay context

210 activity records
Assay familybiochemical
Systemcell_based
Readout% Inhibition
TargetCRBN
E3CRBN
OrganismHomo sapiens
TechnologyHTRF
Detection targetcell_inhibition
Activity compounds and values

Activity records

210 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C030393
% Inhibition-=70-80%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000095PGDB_C030393PGDB_AS001031View
2D structure for PGDB_C030490
% Inhibition-=60-70%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000217PGDB_C030490PGDB_AS001031View
2D structure for PGDB_C030430
% Inhibition-=90-100%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000256PGDB_C030430PGDB_AS001031View
2D structure for PGDB_C030481
% Inhibition-=80-90%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000329PGDB_C030481PGDB_AS001031View
2D structure for PGDB_C030425
% Inhibition-=80-90%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000447PGDB_C030425PGDB_AS001031View
2D structure for PGDB_C030470
% Inhibition-=80-90%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000483PGDB_C030470PGDB_AS001031View
2D structure for PGDB_C030556
% Inhibition-=80-90%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000497PGDB_C030556PGDB_AS001031View
2D structure for PGDB_C030341
% Inhibition-=80-90%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000535PGDB_C030341PGDB_AS001031View
2D structure for PGDB_C030418
% Inhibition-=90-100%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000536PGDB_C030418PGDB_AS001031View
2D structure for PGDB_C030539
% Inhibition-=60-70%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000584PGDB_C030539PGDB_AS001031View
2D structure for PGDB_C030469
% Inhibition-=60-70%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000627PGDB_C030469PGDB_AS001031View
2D structure for PGDB_C030520
% Inhibition-=70-80%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000697PGDB_C030520PGDB_AS001031View
2D structure for PGDB_C030433
% Inhibition-=70-80%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000738PGDB_C030433PGDB_AS001031View
2D structure for PGDB_C030300
% Inhibition-=70-80%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000776PGDB_C030300PGDB_AS001031View
2D structure for PGDB_C030403
% Inhibition-=90-100%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000882PGDB_C030403PGDB_AS001031View
2D structure for PGDB_C030560
% Inhibition-=90-100%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000927PGDB_C030560PGDB_AS001031View
2D structure for PGDB_C030287
% Inhibition-=80-90%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000964PGDB_C030287PGDB_AS001031View
2D structure for PGDB_C030304
% Inhibition-=90-100%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000975PGDB_C030304PGDB_AS001031View
2D structure for PGDB_C030278
% Inhibition-=80-90%2 uM-CRBNCRBN-WO2026061475A1PGDB_A000997PGDB_C030278PGDB_AS001031View
2D structure for PGDB_C030449
% Inhibition-=90-100%2 uM-CRBNCRBN-WO2026061475A1PGDB_A001233PGDB_C030449PGDB_AS001031View
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