Activity record

PGDB_A079390

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 11.3 nM

E3 ligaseCRBN
Cell lineLS513
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001452
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031944
Compound IDPGDB_C031944
CompoundI-4
Source record IDPGDB_C031944
InChIKeyVJXGXHFTYUGDLM-NZONHHAESA-N

Assay context

Assay IDPGDB_AS001452
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineLS513
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-4

I-4 enlarged structureI-4 location on patent page 247
Activity table
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