Activity record

PGDB_A079507

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 179.7 nM

E3 ligaseCRBN
Cell lineLS513
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001452
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031963
Compound IDPGDB_C031963
CompoundI-23
Source record IDPGDB_C031963
InChIKeyKODIQUYYMUAFTC-WTGCYTDFSA-N

Assay context

Assay IDPGDB_AS001452
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineLS513
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-23

I-23 enlarged structureI-23 location on patent page 251
Activity table
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