Activity record

PGDB_A079865

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 0.11 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000447
PatentWO2026103798A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031397
Compound IDPGDB_C031397
Compound实施例 88
Source record IDPGDB_C031397
InChIKeyIUFOLRXLKLUDCV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000447
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2026103798A1
Compound location

实施例 88

实施例 88 enlarged structure实施例 88 location on patent page 85
Activity table
Page 89 · table single