Assay

PGDB_AS000447

System: biochemicalTarget: CRBN
Assay context summary

Assay context

8 activity records
Assay familybiochemical
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
OrganismHomo sapiens
TechnologyHTRF
Activity compounds and values

Activity records

8 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C031402
IC50-=12.8uM-—CRBNCRBN-WO2026103798A1PGDB_A000959PGDB_C031402PGDB_AS000447View
2D structure for PGDB_C031332
IC50-=0.17uM-—CRBNCRBN-WO2026103798A1PGDB_A001305PGDB_C031332PGDB_AS000447View
2D structure for PGDB_C031331
IC50-=0.24uM-—CRBNCRBN-WO2026103798A1PGDB_A004445PGDB_C031331PGDB_AS000447View
2D structure for PGDB_C009208
IC50-=1.29uM-—CRBNCRBN-WO2026103798A1PGDB_A004662PGDB_C009208PGDB_AS000447View
2D structure for PGDB_C031399
IC50-=12.95uM-—CRBNCRBN-WO2026103798A1PGDB_A006896PGDB_C031399PGDB_AS000447View
2D structure for PGDB_C031397
IC50-=0.11uM-—CRBNCRBN-WO2026103798A1PGDB_A079865PGDB_C031397PGDB_AS000447View
2D structure for PGDB_C031363
IC50-=0.2uM-—CRBNCRBN-WO2026103798A1PGDB_A080241PGDB_C031363PGDB_AS000447View
2D structure for PGDB_C031403
IC50-=0.15uM-—CRBNCRBN-WO2026103798A1PGDB_A081814PGDB_C031403PGDB_AS000447View
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