Activity record

PGDB_A080210

Assay: % DegradationTarget: KRASQC: ambiguous
Activity overview

DC50 = 1.4 nM

TargetKRAS
Time18 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001045
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031968
Compound IDPGDB_C031968
CompoundI-28
Source record IDPGDB_C031968
InChIKeySOSZWLMLFZNYDD-BIJCWAAXSA-N

Assay context

Assay IDPGDB_AS001045
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time18 h
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-28

I-28 enlarged structureI-28 location on patent page 264
Activity table
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