Activity record

PGDB_A080552

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

DC50 = 3.981071705534969 nM

TargetCDK2
Cell lineHEK293T
Time6-hour
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001728
PatentWO2026064643A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C030653
Compound IDPGDB_C030653
Compound4;Ex 4
Source record IDPGDB_C030653
InChIKeyOXSUBSHPYMMLKE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001728
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time6-hour
TargetCDK2
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDWO2026064643A1
Compound location

4;Ex 4

4;Ex 4 enlarged structure4;Ex 4 location on patent page 111
Activity table
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