Activity record

PGDB_A083449

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 60-80 %

TargetCRBN
E3 ligaseCRBN
Concentration2 uM
Time3 h
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS002552
PatentCN119654316A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C022247
Compound IDPGDB_C022247
CompoundGT-08861
Source record IDPGDB_C022247
InChIKeyCLLNCPQKDRKVQT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002552
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration2 uM
Treatment time3 h
Detection targetcell_inhibition
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDCN119654316A