PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

189 activity records

Assay familyternary_complex

Systembiochemical

ReadoutFold change

TargetCRBN | DDB1

E3CRBN | DDB1

Activity compounds and values

Activity records

189 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
EC50	-	=	10-100	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A007010	PGDB_C012312	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A007488	PGDB_C012321	PGDB_AS000738	View
EC50	-	=	10-100	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A008248	PGDB_C012362	PGDB_AS000738	View
EC50	-	>	1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A008308	PGDB_C012418	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A008697	PGDB_C012454	PGDB_AS000738	View
EC50	-	>	1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A008722	PGDB_C012363	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A009209	PGDB_C012319	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A009384	PGDB_C012373	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A010548	PGDB_C012317	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A011029	PGDB_C012386	PGDB_AS000738	View
EC50	-	>	1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A013071	PGDB_C012359	PGDB_AS000738	View
EC50	-	>	1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A013389	PGDB_C012412	PGDB_AS000738	View
EC50	-	=	10-100	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A013437	PGDB_C012369	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A014654	PGDB_C012436	PGDB_AS000738	View
EC50	-	=	10-100	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A014677	PGDB_C012370	PGDB_AS000738	View
EC50	-	=	10-100	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A015261	PGDB_C012294	PGDB_AS000738	View
EC50	-	=	10-100	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A015411	PGDB_C012394	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A015721	PGDB_C012377	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A016065	PGDB_C012443	PGDB_AS000738	View
EC50	-	=	100-1000	nM	-	—	ALK	CRBN	-	WO2026015344A1	PGDB_A016136	PGDB_C012398	PGDB_AS000738	View

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