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Compound
PGDB_C012312
8 activity records1 related patents
2D structure
O=C1CCC(N2C(=O)C3=C(C2=O)N(Cc2nc(-c4cccc(Br)c4F)no2)CCC3)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 10-100 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A007010 | PGDB_C012312 | PGDB_AS000738 | View |
| Emax | - | > | 120 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A013947 | PGDB_C012312 | PGDB_AS001094 | View |
| Emax | - | > | 120 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A016510 | PGDB_C012312 | PGDB_AS001769 | View |
| EC50 | - | < | 10 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A020216 | PGDB_C012312 | PGDB_AS002152 | View |
| Emax | - | = | 50-120 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A051077 | PGDB_C012312 | PGDB_AS001094 | View |
| EC50 | - | = | 10-100 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A057298 | PGDB_C012312 | PGDB_AS002152 | View |
| EC50 | - | = | 100-1000 | nM | - | — | ALK | CRBN | - | WO2026015344A1 | PGDB_A066828 | PGDB_C012312 | PGDB_AS000738 | View |
| Emax | - | > | 120 | % | - | 2 h | ALK | CRBN | - | WO2026015344A1 | PGDB_A075020 | PGDB_C012312 | PGDB_AS001769 | View |