Assay

PGDB_AS000852

System: cell_basedTarget: IKZF2Cell line: 293GT
Assay context summary

Assay context

20 activity records
Assay family% Degradation
Systemcell_based
ReadoutAC50
TargetIKZF2
E3Not specified
Cell line293GT
Detection targetprotein_degradation
Activity compounds and values

Activity records

20 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C006511
AC50-=13.1uM-—IKZF2-293GTCN113490528APGDB_A007495PGDB_C006511PGDB_AS000852View
2D structure for PGDB_C006501
AC50-=0.079uM-—IKZF2-293GTCN113490528APGDB_A007621PGDB_C006501PGDB_AS000852View
2D structure for PGDB_C006513
AC50-=10uM-—IKZF2-293GTCN113490528APGDB_A008214PGDB_C006513PGDB_AS000852View
2D structure for PGDB_C006508
AC50-=2.2uM-—IKZF2-293GTCN113490528APGDB_A025125PGDB_C006508PGDB_AS000852View
2D structure for PGDB_C006515
AC50-=0.017uM-—IKZF2-293GTCN113490528APGDB_A027108PGDB_C006515PGDB_AS000852View
2D structure for PGDB_C006503
AC50-=0.014uM-—IKZF2-293GTCN113490528APGDB_A027624PGDB_C006503PGDB_AS000852View
2D structure for PGDB_C006514
AC50-=1.87uM-—IKZF2-293GTCN113490528APGDB_A037805PGDB_C006514PGDB_AS000852View
2D structure for PGDB_C006512
AC50-=2.86uM-—IKZF2-293GTCN113490528APGDB_A041423PGDB_C006512PGDB_AS000852View
2D structure for PGDB_C006507
AC50-=0.038uM-—IKZF2-293GTCN113490528APGDB_A047519PGDB_C006507PGDB_AS000852View
2D structure for PGDB_C006496
AC50-=0.02uM-—IKZF2-293GTCN113490528APGDB_A048003PGDB_C006496PGDB_AS000852View
2D structure for PGDB_C006505
AC50-=0.024uM-—IKZF2-293GTCN113490528APGDB_A049401PGDB_C006505PGDB_AS000852View
2D structure for PGDB_C006502
AC50-=0.092uM-—IKZF2-293GTCN113490528APGDB_A049815PGDB_C006502PGDB_AS000852View
2D structure for PGDB_C006517
AC50-=0.14uM-—IKZF2-293GTCN113490528APGDB_A056813PGDB_C006517PGDB_AS000852View
2D structure for PGDB_C006498
AC50-=1.73uM-—IKZF2-293GTCN113490528APGDB_A064286PGDB_C006498PGDB_AS000852View
2D structure for PGDB_C006504
AC50-=0.025uM-—IKZF2-293GTCN113490528APGDB_A066805PGDB_C006504PGDB_AS000852View
2D structure for PGDB_C006497
AC50-=0.012uM-—IKZF2-293GTCN113490528APGDB_A072498PGDB_C006497PGDB_AS000852View
2D structure for PGDB_C006506
AC50-=0.009uM-—IKZF2-293GTCN113490528APGDB_A075140PGDB_C006506PGDB_AS000852View
2D structure for PGDB_C006516
AC50-=0.019uM-—IKZF2-293GTCN113490528APGDB_A075550PGDB_C006516PGDB_AS000852View
2D structure for PGDB_C006495
AC50-=0.089uM-—IKZF2-293GTCN113490528APGDB_A076603PGDB_C006495PGDB_AS000852View
2D structure for PGDB_C006500
AC50-=0.064uM-—IKZF2-293GTCN113490528APGDB_A077841PGDB_C006500PGDB_AS000852View
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