Assay

PGDB_AS002416

System: biochemicalTarget: CRBN
Assay context summary

Assay context

36 activity records
Assay familybinding
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
Activity compounds and values

Activity records

36 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C025568
IC50-=95.49925860214368nM-—---EP4683934A1PGDB_A008085PGDB_C025568PGDB_AS002416View
2D structure for PGDB_C025580
IC50-=138.03842646028838nM-—---EP4683934A1PGDB_A008162PGDB_C025580PGDB_AS002416View
2D structure for PGDB_C025577
IC50-=16.595869074375596nM-—---EP4683934A1PGDB_A016139PGDB_C025577PGDB_AS002416View
2D structure for PGDB_C025578
IC50-=16.218100973589298nM-—---EP4683934A1PGDB_A016227PGDB_C025578PGDB_AS002416View
2D structure for PGDB_C025573
IC50-=100nM-—---EP4683934A1PGDB_A018592PGDB_C025573PGDB_AS002416View
2D structure for PGDB_C025572
IC50-=87.09635899560814nM-—---EP4683934A1PGDB_A019441PGDB_C025572PGDB_AS002416View
2D structure for PGDB_C025584
IC50-=58.88436553555884nM-—---EP4683934A1PGDB_A025550PGDB_C025584PGDB_AS002416View
2D structure for PGDB_C025583
IC50-=263.02679918953817nM-—---EP4683934A1PGDB_A026811PGDB_C025583PGDB_AS002416View
2D structure for PGDB_C025594
IC50-=22.38721138568338nM-—---EP4683934A1PGDB_A027178PGDB_C025594PGDB_AS002416View
2D structure for PGDB_C025585
IC50-=162.18100973589299nM-—---EP4683934A1PGDB_A029328PGDB_C025585PGDB_AS002416View
2D structure for PGDB_C025581
IC50-=338.84415613920277nM-—---EP4683934A1PGDB_A029474PGDB_C025581PGDB_AS002416View
2D structure for PGDB_C025569
IC50-=83.17637711026708nM-—---EP4683934A1PGDB_A029495PGDB_C025569PGDB_AS002416View
2D structure for PGDB_C025574
IC50-=109.64781961431851nM-—---EP4683934A1PGDB_A029924PGDB_C025574PGDB_AS002416View
2D structure for PGDB_C025589
IC50-=24.547089156850287nM-—---EP4683934A1PGDB_A030089PGDB_C025589PGDB_AS002416View
2D structure for PGDB_C025588
IC50-=478.630092322638nM-—---EP4683934A1PGDB_A032002PGDB_C025588PGDB_AS002416View
2D structure for PGDB_C009601
IC50-=64.56542290346549nM-—---EP4683934A1PGDB_A034803PGDB_C009601PGDB_AS002416View
2D structure for PGDB_C025579
IC50-=186.20871366628657nM-—---EP4683934A1PGDB_A035758PGDB_C025579PGDB_AS002416View
2D structure for PGDB_C025575
IC50-=100nM-—---EP4683934A1PGDB_A037241PGDB_C025575PGDB_AS002416View
2D structure for PGDB_C025566
IC50-=26.91534803926914nM-—---EP4683934A1PGDB_A038449PGDB_C025566PGDB_AS002416View
2D structure for PGDB_C025576
IC50-=33.884415613920275nM-—---EP4683934A1PGDB_A043336PGDB_C025576PGDB_AS002416View
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