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Compound
PGDB_C006053
6 activity records2 related patents
2D structure
O=C1CC[C@H](N2C(=O)c3cccc4c(Cc5ccc(CN6CCOCC6)cc5)ccc2c34)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.033-0.149 | nM | - | — | IKZF1 | - | NCI-H929 | CA3173658A1 | PGDB_A020043 | PGDB_C006053 | PGDB_AS001574 | View |
| IC50 | - | = | 0.27 | nM | - | — | IKZF1 | - | - | CA3173658A1 | PGDB_A024467 | PGDB_C006053 | PGDB_AS000746 | View |
| GI50 | - | < | 1 | nM | - | — | - | - | NCI-H929 | EA048567B1 | PGDB_A026807 | PGDB_C006053 | PGDB_AS000655 | View |
| IC50 | - | = | 0.071 | nM | - | — | IKZF1 | - | NCI-H929 | CA3173658A1 | PGDB_A033512 | PGDB_C006053 | PGDB_AS000269 | View |
| Emax | - | = | 22.4 | % | 1 uM | 55.7 ± 6.0 | 22.4 ± 3.1 | IKZF1 | - | - | CA3173658A1 | PGDB_A052717 | PGDB_C006053 | PGDB_AS001198 | View |
| Emax | - | = | 4 | % | 1 uM | 97 - 204 | 0.033 - 0.149 | IKZF1 | - | NCI-H929 | CA3173658A1 | PGDB_A063927 | PGDB_C006053 | PGDB_AS002447 | View |