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Compound
PGDB_C007560
4 activity records1 related patents
2D structure
N#Cc1ccc(N2CCN(Cc3ccc(Cc4ccc5c6c(cc(Br)cc46)C(=O)N5C4CCC(=O)NC4=O)cc3)CC2)c(F)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 92.2 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A010940 | PGDB_C007560 | PGDB_AS002293 | View |
| DC50 | - | = | 1.23 | nM | - | — | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A017961 | PGDB_C007560 | PGDB_AS002064 | View |
| DC50 | - | = | 0.772 | uM | - | — | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A046231 | PGDB_C007560 | PGDB_AS002491 | View |
| Dmax | - | = | 65.8 | % | Concentration context: HiBiT SALL4: D max (%) | 20 h | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A055376 | PGDB_C007560 | PGDB_AS000801 | View |