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Compound
PGDB_C010137
3 activity records1 related patents
2D structure
Cc1ccc(-c2nnc(N[C@H]3CN(c4cc(F)c(C5CCC(=O)NC5=O)c(F)c4)[C@@H]3C)o2)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 4.8 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025090727A1 | PGDB_A015455 | PGDB_C010137 | PGDB_AS001842 | View |
| DC50 | - | = | 87.4 | nM | - | — | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A068469 | PGDB_C010137 | PGDB_AS001688 | View |
| Dmax | - | = | 59.4 | % | - | 24 h | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A071066 | PGDB_C010137 | PGDB_AS002016 | View |