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Compound
PGDB_C010139
3 activity records1 related patents
2D structure
C[C@@H]1[C@@H](Nc2nnc(C34CC(C(F)(F)F)(C3)C4)o2)CN1c1cc(F)c(C2CCC(=O)NC2=O)c(F)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 46.5 | nM | - | — | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A013211 | PGDB_C010139 | PGDB_AS001688 | View |
| Dmax | - | = | 9.9 | % | - | 24 h | GSPT1 | - | HEK293 | WO2025090727A1 | PGDB_A032781 | PGDB_C010139 | PGDB_AS001842 | View |
| Dmax | - | = | 62 | % | - | 24 h | CDK2 | - | HEK293 | WO2025090727A1 | PGDB_A048059 | PGDB_C010139 | PGDB_AS002016 | View |