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Compound
PGDB_C012523
4 activity records1 related patents
2D structure
N#Cc1cc(-n2cc(CN3CC[C@H](Oc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)C3)cn2)ccc1OC(F)(F)FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.0123 | uM | - | — | WEE1 | - | LentiX-oeWEE1-ePL | WO2026030657A1 | PGDB_A013405 | PGDB_C012523 | PGDB_AS000951 | View |
| EC50 | - | = | 0.0059 | uM | - | — | WEE1 | - | MKN45 | WO2026030657A1 | PGDB_A015927 | PGDB_C012523 | PGDB_AS002574 | View |
| Ymin | - | = | 8.78 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | WO2026030657A1 | PGDB_A044438 | PGDB_C012523 | PGDB_AS000093 | View |
| Ymin | - | = | 33 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | LentiX-oeWEE1-ePL | WO2026030657A1 | PGDB_A047072 | PGDB_C012523 | PGDB_AS000656 | View |