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Compound
PGDB_C012537
4 activity records1 related patents
2D structure
COc1cc(-n2cc(CN3CC[C@H](Oc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)C3)cn2)ccn1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ymin | - | = | 28.82 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | LentiX-oeWEE1-ePL | WO2026030657A1 | PGDB_A014771 | PGDB_C012537 | PGDB_AS000656 | View |
| Ymin | - | = | 14.71 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | WO2026030657A1 | PGDB_A028818 | PGDB_C012537 | PGDB_AS000093 | View |
| EC50 | - | = | 0.0207 | uM | - | — | WEE1 | - | LentiX-oeWEE1-ePL | WO2026030657A1 | PGDB_A036934 | PGDB_C012537 | PGDB_AS000951 | View |
| EC50 | - | = | 0.0647 | uM | - | — | WEE1 | - | MKN45 | WO2026030657A1 | PGDB_A039685 | PGDB_C012537 | PGDB_AS002574 | View |