PatGlueDB | Molecular Glue Patent Bioactivity Database

2D structure

COc1cccc2cc(C(=O)NCc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)oc12

Compound summary

Compound IDPGDB_C019857

FormulaC24H21N3O6

Molecular weight447.447

InChIKeyCATYQLNFTHUELV-UHFFFAOYSA-N

Physicochemical properties

Exact mass447.143

RDKit cLogP2.13

TPSA118

HBD / HBA2 / 6

Rotatable bonds5

Heavy atoms33

Hetero atoms9

Rings / aromatic5 / 3

Fraction Csp30.25

Formal charge0

Fragments1

Activity compounds and values

Activity records

6 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
% Cell viability	-	=	17.61	%	500 nM	72 h	-	-	NCI-H1155	KR102823538B1	PGDB_A017169	PGDB_C019857	PGDB_AS000424	View
% Cell viability	-	=	38.98	%	10 nM	72 h	-	-	NCI-H1155	KR2023068335	PGDB_A037662	PGDB_C019857	PGDB_AS001333	View
% Cell viability	-	=	38.98	%	10 nM	72 h	GSPT1	CRBN	NCI-H1155	CN118234721A	PGDB_A059421	PGDB_C019857	PGDB_AS001120	View
% Cell viability	-	=	38.98	%	10 nM	72 h	-	-	NCI-H1155	KR102823538B1	PGDB_A059720	PGDB_C019857	PGDB_AS000439	View
% Cell viability	-	=	17.61	%	500 nM	72 h	-	-	NCI-H1155	KR2023068335	PGDB_A062357	PGDB_C019857	PGDB_AS001738	View
% Cell viability	-	=	17.61	%	500 nM	72 h	GSPT1	CRBN	NCI-H1155	CN118234721A	PGDB_A065377	PGDB_C019857	PGDB_AS001755	View

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