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Compound
PGDB_C022007
12 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCN(c5cccc6sccc56)CC4)ccc3C2=S)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-80 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A082515 | PGDB_C022007 | PGDB_AS000660 | View |
| IC50 | - | > | 10 | nM | - | — | - | - | MM.1S | CN119654316A | PGDB_A082587 | PGDB_C022007 | PGDB_AS001506 | View |
| IC50 | - | > | 100 | nM | - | — | - | - | MGC-803 | CN119654316A | PGDB_A083308 | PGDB_C022007 | PGDB_AS002336 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A083359 | PGDB_C022007 | PGDB_AS001680 | View |
| % Degradation | - | = | 0-80 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A083397 | PGDB_C022007 | PGDB_AS001023 | View |
| IC50 | - | > | 50 | nM | - | — | - | - | H1975 | CN119654316A | PGDB_A083895 | PGDB_C022007 | PGDB_AS002346 | View |
| IC50 | - | > | 50 | nM | - | — | - | - | Jurkat | CN119654316A | PGDB_A084296 | PGDB_C022007 | PGDB_AS002479 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A084710 | PGDB_C022007 | PGDB_AS000466 | View |
| IC50 | - | > | 10 | nM | - | — | - | - | JeKo-1 | CN119654316A | PGDB_A085279 | PGDB_C022007 | PGDB_AS000137 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A085281 | PGDB_C022007 | PGDB_AS002430 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A085602 | PGDB_C022007 | PGDB_AS000017 | View |
| IC50 | - | > | 100 | nM | - | — | - | - | MCF-7 | CN119654316A | PGDB_A085690 | PGDB_C022007 | PGDB_AS001496 | View |