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Compound
PGDB_C022019
12 activity records1 related patents
2D structure
O=C1CCC(N2CC/C=C(CN3CCC(c4cccc(Cl)c4Cl)CC3)\C=C/CC2=S)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | > | 100 | nM | - | — | - | - | MGC-803 | CN119654316A | PGDB_A081939 | PGDB_C022019 | PGDB_AS002336 | View |
| IC50 | - | > | 50 | nM | - | — | - | - | JeKo-1 | CN119654316A | PGDB_A082226 | PGDB_C022019 | PGDB_AS000137 | View |
| % Degradation | - | = | 0-80 | % | - | - | GSPT1 | - | - | CN119654316A | PGDB_A082335 | PGDB_C022019 | PGDB_AS000660 | View |
| % Degradation | - | = | 0-80 | % | - | - | WEE1 | - | - | CN119654316A | PGDB_A082651 | PGDB_C022019 | PGDB_AS001023 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF2 | - | - | CN119654316A | PGDB_A082811 | PGDB_C022019 | PGDB_AS002430 | View |
| % Degradation | - | = | 80-100 | % | - | - | - | - | - | CN119654316A | PGDB_A082908 | PGDB_C022019 | PGDB_AS000466 | View |
| IC50 | - | > | 50 | nM | - | — | - | - | H1975 | CN119654316A | PGDB_A083027 | PGDB_C022019 | PGDB_AS002346 | View |
| IC50 | - | > | 10 | nM | - | — | - | - | Jurkat | CN119654316A | PGDB_A083600 | PGDB_C022019 | PGDB_AS002479 | View |
| % Degradation | - | = | 80-100 | % | - | - | IKZF3 | - | - | CN119654316A | PGDB_A084124 | PGDB_C022019 | PGDB_AS000017 | View |
| % Degradation | - | = | 0-80 | % | - | - | IKZF1 | - | - | CN119654316A | PGDB_A084280 | PGDB_C022019 | PGDB_AS001680 | View |
| IC50 | - | > | 100 | nM | - | — | - | - | MCF-7 | CN119654316A | PGDB_A084815 | PGDB_C022019 | PGDB_AS001496 | View |
| IC50 | - | > | 5 | nM | - | — | - | - | MM.1S | CN119654316A | PGDB_A085251 | PGDB_C022019 | PGDB_AS001506 | View |