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COc1cc(C)nc2ccc(CN3CC[C@H](Oc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)C3)cc12| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ymin | - | = | 47.92 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | CN119325469A | PGDB_A007697 | PGDB_C023200 | PGDB_AS000567 | View | |
| EC50 | - | = | 1.498301 | uM | - | — | WEE1 | - | MKN45 | CN119325469A | PGDB_A019069 | PGDB_C023200 | PGDB_AS001345 | View | |
| % Degradation | - | = | 55.62 | % | Concentration range: 10 uM | 4 h | WEE1 | - | HEK293T | CN119325469A | PGDB_A049897 | PGDB_C023200 | PGDB_AS001384 | View | |
| EC50 | - | = | 0.0268145 | uM | - | — | WEE1 | - | HEK293T | CN119325469A | PGDB_A076997 | PGDB_C023200 | PGDB_AS001487 | View |