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Compound
PGDB_C023362
4 activity records1 related patents
2D structure
COC(C)(C)c1ccc2cc(CN3CC[C@H](Oc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)C3)ncc2c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ymin | - | = | 11.51 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | CN119325469A | PGDB_A009544 | PGDB_C023362 | PGDB_AS000567 | View |
| % Degradation | - | = | 68 | % | Concentration range: 10 uM | 4 h | WEE1 | - | HEK293T | CN119325469A | PGDB_A019072 | PGDB_C023362 | PGDB_AS001384 | View |
| EC50 | - | = | 0.001207 | uM | - | — | WEE1 | - | HEK293T | CN119325469A | PGDB_A052739 | PGDB_C023362 | PGDB_AS001487 | View |
| EC50 | - | = | 0.00604 | uM | - | — | WEE1 | - | MKN45 | CN119325469A | PGDB_A061988 | PGDB_C023362 | PGDB_AS001345 | View |