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Compound
PGDB_C023412
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(O[C@H]4CCN(Cc5ccc6nc(N7CCC(F)(F)CC7)ccc6c5)C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ymin | - | = | 17.9 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | CN119325469A | PGDB_A007909 | PGDB_C023412 | PGDB_AS000567 | View |
| EC50 | - | = | 0.038423506 | uM | - | — | WEE1 | - | HEK293T | CN119325469A | PGDB_A022866 | PGDB_C023412 | PGDB_AS001487 | View |
| EC50 | - | = | 0.017852 | uM | - | — | WEE1 | - | MKN45 | CN119325469A | PGDB_A032970 | PGDB_C023412 | PGDB_AS001345 | View |
| % Degradation | - | = | 78.37800026 | % | Concentration range: 10 uM | 4 h | WEE1 | - | HEK293T | CN119325469A | PGDB_A061825 | PGDB_C023412 | PGDB_AS001384 | View |