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O=C1CCC(N2Cc3cc(O[C@@H]4CN(Cc5ccc6nc([C@H]7CCOC7)ccc6c5)CC4(F)F)ccc3C2=O)C(=O)N1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 69.19099426 | % | Concentration range: 10 uM | 4 h | WEE1 | - | HEK293T | CN119325469A | PGDB_A009726 | PGDB_C023472 | PGDB_AS001384 | View | |
| EC50 | - | = | 0.008494974 | uM | - | — | WEE1 | - | HEK293T | CN119325469A | PGDB_A012929 | PGDB_C023472 | PGDB_AS001487 | View | |
| EC50 | - | = | 0.008422224 | uM | - | — | WEE1 | - | MKN45 | CN119325469A | PGDB_A048155 | PGDB_C023472 | PGDB_AS001345 | View | |
| Ymin | - | = | 8.764418788 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | CN119325469A | PGDB_A068151 | PGDB_C023472 | PGDB_AS000567 | View |