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Compound
PGDB_C024583
5 activity records1 related patents
2D structure
CCC(C)OCC#Cc1cnc([C@H](C)OC)c(/C2=C3\c4cc(ccc4N3CC)-c3csc(n3)CC(NC(=O)C3C[C@H]3C)C(=O)N3CCCC(N3)C(=O)OCC(C)(C)C2)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 10 | nM | - | — | - | - | MIA PaCa-2 | CN121181579A | PGDB_A015929 | PGDB_C024583 | PGDB_AS001225 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | NCI-H358 | CN121181579A | PGDB_A029347 | PGDB_C024583 | PGDB_AS000504 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | HPAC | CN121181579A | PGDB_A035110 | PGDB_C024583 | PGDB_AS000097 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | AsPC-1 | CN121181579A | PGDB_A042646 | PGDB_C024583 | PGDB_AS001095 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | AGS | CN121181579A | PGDB_A046438 | PGDB_C024583 | PGDB_AS000586 | View |