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Compound
PGDB_C024592
5 activity records1 related patents
2D structure
CCn1c(-c2cc(C#CC(C)(O)C3CCOCC3)cnc2C(C)OC)c2c3cc(ccc31)-c1csc(n1)CC(NC(=O)C1CC1C)C(=O)N1NC(C(=O)OCC(C)(C)C2)C2CC1C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 10 | nM | - | — | - | - | MIA PaCa-2 | CN121181579A | PGDB_A012754 | PGDB_C024592 | PGDB_AS001225 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | AGS | CN121181579A | PGDB_A013397 | PGDB_C024592 | PGDB_AS000586 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | HPAC | CN121181579A | PGDB_A026732 | PGDB_C024592 | PGDB_AS000097 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | AsPC-1 | CN121181579A | PGDB_A027739 | PGDB_C024592 | PGDB_AS001095 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | NCI-H358 | CN121181579A | PGDB_A072676 | PGDB_C024592 | PGDB_AS000504 | View |