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Compound
PGDB_C024659
3 activity records1 related patents
2D structure
CC(C)[C@@H](C(=O)N[C@H]1C[C@H]2CN(CCO2)c2ccc3c(c2)c2c(n3CC(F)(F)F)/C=C(C#CC(C)(C)C(=O)N3CCN(C)CC3)\C=N/N[C@@H]3CN(C1=O)/C3=C\N1CC1C(=O)OCC(C)(C)C2)N1CC[C@]2(CCN(C(=O)[C@H]3[C@@H]4C[C@@H]4N3C)C2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | HPAC | CN121181579A | PGDB_A016884 | PGDB_C024659 | PGDB_AS000097 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | AsPC-1 | CN121181579A | PGDB_A034263 | PGDB_C024659 | PGDB_AS001095 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | AGS | CN121181579A | PGDB_A066161 | PGDB_C024659 | PGDB_AS000586 | View |