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Compound
PGDB_C024679
5 activity records1 related patents
2D structure
CCN(C)C(=O)C(C)(C)C#Cc1cnc(C(C)OC)c(-c2c3n(CC(F)(F)F)c4ccc(cc24)-c2csc(n2)CC(NC(=O)C2C(C)C2C)C(=O)N2NC(C(=O)OCC(C)(C)C3)C3CC2C3)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | HPAC | CN121181579A | PGDB_A007931 | PGDB_C024679 | PGDB_AS000097 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | AGS | CN121181579A | PGDB_A026854 | PGDB_C024679 | PGDB_AS000586 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | NCI-H358 | CN121181579A | PGDB_A045433 | PGDB_C024679 | PGDB_AS000504 | View |
| IC50 | - | <= | 10 | nM | - | — | - | - | MIA PaCa-2 | CN121181579A | PGDB_A064511 | PGDB_C024679 | PGDB_AS001225 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | AsPC-1 | CN121181579A | PGDB_A076232 | PGDB_C024679 | PGDB_AS001095 | View |