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Compound
PGDB_C025835
5 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCN(c5ccc(Nc6ncc7nc(Nc8ccccc8)n(C8CCCC8)c7n6)cc5)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | < | 50 | nM | - | — | EGFR | - | PC-9 | CN116239566A | PGDB_A007776 | PGDB_C025835 | PGDB_AS000044 | View |
| IC50 | - | = | 1000-5000 | nM | - | — | EGFR | - | CCRF-CEM | CN116239566A | PGDB_A012783 | PGDB_C025835 | PGDB_AS000005 | View |
| IC50 | - | = | 50-100 | nM | - | — | EGFR | - | NCI-H358 | CN116239566A | PGDB_A016536 | PGDB_C025835 | PGDB_AS000770 | View |
| IC50 | - | = | 100-500 | nM | - | — | EGFR | - | HCC827 | CN116239566A | PGDB_A030968 | PGDB_C025835 | PGDB_AS002229 | View |
| IC50 | - | = | 1000-5000 | nM | - | — | EGFR | - | Mino | CN116239566A | PGDB_A045886 | PGDB_C025835 | PGDB_AS000353 | View |