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Compound
PGDB_C025851
4 activity records1 related patents
2D structure
COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CN1CCN(Cc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | < | 50 | nM | - | — | EGFR | - | HCC827 | CN116239566A | PGDB_A010224 | PGDB_C025851 | PGDB_AS002229 | View |
| IC50 | - | = | 1000-5000 | nM | - | — | EGFR | - | Mino | CN116239566A | PGDB_A060885 | PGDB_C025851 | PGDB_AS000353 | View |
| IC50 | - | < | 50 | nM | - | — | EGFR | - | NCI-H358 | CN116239566A | PGDB_A071014 | PGDB_C025851 | PGDB_AS000770 | View |
| IC50 | - | < | 50 | nM | - | — | EGFR | - | PC-9 | CN116239566A | PGDB_A073765 | PGDB_C025851 | PGDB_AS000044 | View |