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Compound
PGDB_C025886
9 activity records1 related patents
2D structure
Cc1ccc(C(=O)Nc2ccc(CN3CCN(Cc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2cccnn12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | < | 50 | nM | - | — | ABL1 | - | Kasumi-1 | CN116239566A | PGDB_A007508 | PGDB_C025886 | PGDB_AS000069 | View |
| IC50 | - | < | 50 | nM | - | — | ABL1 | - | Daudi | CN116239566A | PGDB_A011464 | PGDB_C025886 | PGDB_AS001018 | View |
| IC50 | - | < | 50 | nM | - | — | ABL1 | - | CAL-62 | CN116239566A | PGDB_A014646 | PGDB_C025886 | PGDB_AS000882 | View |
| IC50 | - | = | 500-1000 | nM | - | — | ABL1 | - | CCRF-CEM | CN116239566A | PGDB_A031842 | PGDB_C025886 | PGDB_AS000919 | View |
| IC50 | - | < | 50 | nM | - | — | ABL1 | - | K562 | CN116239566A | PGDB_A034029 | PGDB_C025886 | PGDB_AS002026 | View |
| IC50 | - | < | 50 | nM | - | — | ABL1 | - | Mino | CN116239566A | PGDB_A038446 | PGDB_C025886 | PGDB_AS000379 | View |
| IC50 | - | = | 500-1000 | nM | - | — | ABL1 | - | PC-9 | CN116239566A | PGDB_A051662 | PGDB_C025886 | PGDB_AS001222 | View |
| IC50 | - | < | 50 | nM | - | — | ABL1 | - | CCRF-CEM | CN116239566A | PGDB_A061297 | PGDB_C025886 | PGDB_AS000919 | View |
| IC50 | - | < | 50 | nM | - | — | ABL1 | - | Mino | CN116239566A | PGDB_A065761 | PGDB_C025886 | PGDB_AS000379 | View |