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Compound
PGDB_C025971
6 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCC(n5cc(NC(=O)c6coc(-c7ccnc(NCC8CC8)c7)n6)c(C(F)F)n5)CC4)c(F)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 100-500 | nM | - | — | IRAK4 | - | SU-DHL-4 | CN116239566A | PGDB_A008343 | PGDB_C025971 | PGDB_AS002569 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | SW620 | CN116239566A | PGDB_A017119 | PGDB_C025971 | PGDB_AS000233 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | Jurkat | CN116239566A | PGDB_A029490 | PGDB_C025971 | PGDB_AS000478 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | LNCaP | CN116239566A | PGDB_A030373 | PGDB_C025971 | PGDB_AS000964 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | CCRF-CEM | CN116239566A | PGDB_A034552 | PGDB_C025971 | PGDB_AS001036 | View |
| IC50 | - | < | 50 | nM | - | — | IRAK4 | - | CAL-62 | CN116239566A | PGDB_A070203 | PGDB_C025971 | PGDB_AS000175 | View |