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Compound
PGDB_C028425
5 activity records1 related patents
2D structure
C#Cc1cnc([C@H](C)OC)c(-c2c3c4cc(cc5c4n2CCC5)-c2csc(n2)C[C@H](NC(=O)[C@H]2C[C@@H]2C)C(=O)N2CCC[C@H](N2)C(=O)OCC(C)(C)C3)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | > | 10 | nM | - | — | KRAS | - | HPAC | WO2026047641A1 | PGDB_A007729 | PGDB_C028425 | PGDB_AS001191 | View |
| IC50 | - | > | 10 | nM | - | — | KRAS | - | SW620 | WO2026047641A1 | PGDB_A008904 | PGDB_C028425 | PGDB_AS000598 | View |
| IC50 | - | > | 1 | nM | - | — | KRAS | - | NCI-H358 | WO2026047641A1 | PGDB_A011852 | PGDB_C028425 | PGDB_AS001839 | View |
| IC50 | - | > | 10 | nM | - | — | KRAS | - | AGS | WO2026047641A1 | PGDB_A030246 | PGDB_C028425 | PGDB_AS000159 | View |
| IC50 | - | > | 10 | nM | - | — | KRAS | - | AsPC-1 | WO2026047641A1 | PGDB_A068434 | PGDB_C028425 | PGDB_AS000949 | View |