PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2026047641A1

AssigneeSunrise Oncology Hong Kong

TitleMacrocyclic compounds as ras inhibitors for the treatment of cancer

Family ID97268995

Family members1

Filing year2025

Publication date2026-03-05

JurisdictionWO

Compounds268

Activity records413

Assays5

Activity compounds and values

Activity records

413 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	>	1	nM	-	—	KRAS	-	HPAC	PGDB_A007147	PGDB_C028435	PGDB_AS001191	View
IC50	-	>	1	nM	-	—	KRAS	-	SW620	PGDB_A007291	PGDB_C028603	PGDB_AS000598	View
IC50	-	>	1	nM	-	—	KRAS	-	HPAC	PGDB_A007384	PGDB_C028562	PGDB_AS001191	View
IC50	-	>	1	nM	-	—	KRAS	-	SW620	PGDB_A007443	PGDB_C028673	PGDB_AS000598	View
IC50	-	>	1	nM	-	—	KRAS	-	AsPC-1	PGDB_A007590	PGDB_C028438	PGDB_AS000949	View
IC50	-	>	10	nM	-	—	KRAS	-	HPAC	PGDB_A007729	PGDB_C028425	PGDB_AS001191	View
IC50	-	>	1	nM	-	—	KRAS	-	SW620	PGDB_A007752	PGDB_C028595	PGDB_AS000598	View
IC50	-	>	1	nM	-	—	KRAS	-	HPAC	PGDB_A007830	PGDB_C028540	PGDB_AS001191	View
IC50	-	>	1	nM	-	—	KRAS	-	AsPC-1	PGDB_A007837	PGDB_C028453	PGDB_AS000949	View
IC50	-	>	1	nM	-	—	KRAS	-	SW620	PGDB_A007859	PGDB_C028493	PGDB_AS000598	View
IC50	-	>	1	nM	-	—	KRAS	-	SW620	PGDB_A008157	PGDB_C028524	PGDB_AS000598	View
IC50	-	>	1	nM	-	—	KRAS	-	SW620	PGDB_A008179	PGDB_C028661	PGDB_AS000598	View
IC50	-	>	1	nM	-	—	KRAS	-	SW620	PGDB_A008403	PGDB_C028563	PGDB_AS000598	View
IC50	-	>	10	nM	-	—	KRAS	-	SW620	PGDB_A008480	PGDB_C028483	PGDB_AS000598	View
IC50	-	>	1	nM	-	—	KRAS	-	SW620	PGDB_A008587	PGDB_C028511	PGDB_AS000598	View
IC50	-	>	10	nM	-	—	KRAS	-	AGS	PGDB_A008688	PGDB_C028427	PGDB_AS000159	View
IC50	-	>	1	nM	-	—	KRAS	-	HPAC	PGDB_A008759	PGDB_C028452	PGDB_AS001191	View
IC50	-	>	10	nM	-	—	KRAS	-	SW620	PGDB_A008904	PGDB_C028425	PGDB_AS000598	View
IC50	-	>	10	nM	-	—	KRAS	-	SW620	PGDB_A009107	PGDB_C028488	PGDB_AS000598	View
IC50	-	>	1	nM	-	—	KRAS	-	SW620	PGDB_A009184	PGDB_C028589	PGDB_AS000598	View

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