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Compound
PGDB_C028427
5 activity records1 related patents
2D structure
CO[C@@H](C)c1ncc(C#CC(C)(C)O)cc1-c1c2c3cc(cc4c3n1CCC4)-c1csc(n1)C[C@H](NC(=O)[C@H]1C[C@@H]1C)C(=O)N1CCC[C@H](N1)C(=O)OCC(C)(C)C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | > | 10 | nM | - | — | KRAS | - | AGS | WO2026047641A1 | PGDB_A008688 | PGDB_C028427 | PGDB_AS000159 | View |
| IC50 | - | > | 1 | nM | - | — | KRAS | - | SW620 | WO2026047641A1 | PGDB_A020491 | PGDB_C028427 | PGDB_AS000598 | View |
| IC50 | - | > | 10 | nM | - | — | KRAS | - | HPAC | WO2026047641A1 | PGDB_A036204 | PGDB_C028427 | PGDB_AS001191 | View |
| IC50 | - | > | 10 | nM | - | — | KRAS | - | AsPC-1 | WO2026047641A1 | PGDB_A041803 | PGDB_C028427 | PGDB_AS000949 | View |
| IC50 | - | > | 1 | nM | - | — | KRAS | - | NCI-H358 | WO2026047641A1 | PGDB_A055124 | PGDB_C028427 | PGDB_AS001839 | View |