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Compound
PGDB_C028537
3 activity records1 related patents
2D structure
COC(C)c1ncc(C#C[C@@H](C)N2CCN(C3CC3)CC2)cc1-c1c2c3cc(ccc3n1CC(F)(F)F)N1CCO[C@@H](C[C@H](NC(=O)[C@H](C3CCCC3)N3CC[C@]4(CCN(C(=O)[C@H]5[C@@H](C6CC6)N5C)C4)C3)C(=O)N3CCC[C@H](N3)C(=O)OCC(C)(C)C2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | > | 1 | nM | - | — | KRAS | - | AGS | WO2026047641A1 | PGDB_A018924 | PGDB_C028537 | PGDB_AS000159 | View |
| IC50 | - | > | 1 | nM | - | — | KRAS | - | AsPC-1 | WO2026047641A1 | PGDB_A055069 | PGDB_C028537 | PGDB_AS000949 | View |
| IC50 | - | > | 1 | nM | - | — | KRAS | - | HPAC | WO2026047641A1 | PGDB_A076419 | PGDB_C028537 | PGDB_AS001191 | View |