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Compound
PGDB_C028713
5 activity records1 related patents
2D structure
C=C(C)C#Cc1cc(-c2nc(-c3ccc(-c4ccc5c(c4)n(C)c(=O)n5C4CCC(=O)NC4=O)cc3)n[nH]2)cc2c(Br)c(C(F)(F)P(=O)(O)O)sc12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 92.3 | % | - | - | - | - | HCT116 | WO2026119184 | PGDB_A013554 | PGDB_C028713 | PGDB_AS000959 | View |
| Selectivity index | N2/1B | = | 3.16 | fold | - | — | - | - | HCT116 | WO2026119184 | PGDB_A014603 | PGDB_C028713 | PGDB_AS000119 | View |
| DC50 | - | = | 92.26 | nM | - | — | PTPN1 | - | HCT116 | WO2026119184 | PGDB_A017571 | PGDB_C028713 | PGDB_AS001836 | View |
| DC50 | - | = | 29.11 | nM | - | — | - | - | HCT116 | WO2026119184 | PGDB_A019481 | PGDB_C028713 | PGDB_AS000045 | View |
| Dmax | - | = | 99.5 | % | - | - | - | - | HCT116 | WO2026119184 | PGDB_A060937 | PGDB_C028713 | PGDB_AS000736 | View |