PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberEP3556760A1

AssigneeF Hoffmann La Roche

TitleSpiro compounds

Family ID62027882

Family members1

Filing year2018

Publication date2019-10-23

JurisdictionEP

Compounds22

Activity records22

Assays1

Activity compounds and values

Activity records

22 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
Kd	-	=	0.023	uM	-	—	CRBN	CRBN	-	PGDB_A009560	PGDB_C007393	PGDB_AS000988	View
Kd	-	=	0.017	uM	-	—	CRBN	CRBN	-	PGDB_A012816	PGDB_C007385	PGDB_AS000988	View
Kd	-	=	0.002	uM	-	—	CRBN	CRBN	-	PGDB_A013644	PGDB_C007383	PGDB_AS000988	View
Kd	-	=	0.006	uM	-	—	CRBN	CRBN	-	PGDB_A016107	PGDB_C007403	PGDB_AS000988	View
Kd	-	=	0.006	uM	-	—	CRBN	CRBN	-	PGDB_A017791	PGDB_C007404	PGDB_AS000988	View
Kd	-	=	0.002	uM	-	—	CRBN	CRBN	-	PGDB_A020924	PGDB_C007384	PGDB_AS000988	View
Kd	-	=	0.007	uM	-	—	CRBN	CRBN	-	PGDB_A024556	PGDB_C025999	PGDB_AS000988	View
Kd	-	<	0.001	uM	-	—	CRBN	CRBN	-	PGDB_A030028	PGDB_C026003	PGDB_AS000988	View
Kd	-	=	0.001	uM	-	—	CRBN	CRBN	-	PGDB_A032428	PGDB_C007389	PGDB_AS000988	View
Kd	-	=	0.002	uM	-	—	CRBN	CRBN	-	PGDB_A036296	PGDB_C026001	PGDB_AS000988	View
Kd	-	=	0.016	uM	-	—	CRBN	CRBN	-	PGDB_A042542	PGDB_C007391	PGDB_AS000988	View
Kd	-	=	0.021	uM	-	—	CRBN	CRBN	-	PGDB_A042760	PGDB_C007388	PGDB_AS000988	View
Kd	-	=	0.006	uM	-	—	CRBN	CRBN	-	PGDB_A043155	PGDB_C007396	PGDB_AS000988	View
Kd	-	=	0.028	uM	-	—	CRBN	CRBN	-	PGDB_A047173	PGDB_C007402	PGDB_AS000988	View
Kd	-	=	0.015	uM	-	—	CRBN	CRBN	-	PGDB_A048840	PGDB_C007399	PGDB_AS000988	View
Kd	-	=	0.027	uM	-	—	CRBN	CRBN	-	PGDB_A057013	PGDB_C007387	PGDB_AS000988	View
Kd	-	=	0.006	uM	-	—	CRBN	CRBN	-	PGDB_A066296	PGDB_C007400	PGDB_AS000988	View
Kd	-	<	0.001	uM	-	—	CRBN	CRBN	-	PGDB_A066768	PGDB_C007390	PGDB_AS000988	View
Kd	-	=	0.034	uM	-	—	CRBN	CRBN	-	PGDB_A068908	PGDB_C007386	PGDB_AS000988	View
Kd	-	=	0.011	uM	-	—	CRBN	CRBN	-	PGDB_A071403	PGDB_C011112	PGDB_AS000988	View

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