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Patent
WO2025137053A1
146 compounds841 activity records6 assays
Patent summary
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | EC50 | - | = | 0 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | PGDB_A007011 | PGDB_C011178 | PGDB_AS001798 | View |
 | EC50 | - | = | 0.004 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | PGDB_A007187 | PGDB_C011214 | PGDB_AS001798 | View |
 | Ymin | - | = | 27.8 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | PGDB_A007294 | PGDB_C011139 | PGDB_AS001848 | View |
 | Ymin | - | = | 52.5 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MDA-MB-231 | PGDB_A007512 | PGDB_C011187 | PGDB_AS002525 | View |
 | Ymin | - | = | 10.5 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | PGDB_A007602 | PGDB_C011149 | PGDB_AS000997 | View |
 | EC50 | - | = | 0.002 | uM | - | — | WEE1 | - | MKN45 | PGDB_A007613 | PGDB_C011159 | PGDB_AS002043 | View |
 | EC50 | - | = | 0.014 | uM | - | — | WEE1 | - | MDA-MB-231 | PGDB_A007676 | PGDB_C011208 | PGDB_AS001832 | View |
 | Ymin | - | = | 83.5 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | PGDB_A007744 | PGDB_C011210 | PGDB_AS000997 | View |
 | EC50 | - | = | 0.011 | uM | - | — | WEE1 | - | MDA-MB-231 | PGDB_A007922 | PGDB_C011182 | PGDB_AS001832 | View |
 | EC50 | - | = | 0.1 | uM | - | — | WEE1 | - | MDA-MB-231 | PGDB_A007951 | PGDB_C011157 | PGDB_AS001832 | View |
 | EC50 | - | = | 1.415 | uM | - | — | WEE1 | - | MDA-MB-231 | PGDB_A008049 | PGDB_C011228 | PGDB_AS001832 | View |
 | EC50 | - | = | 0.146 | uM | - | — | WEE1 | - | MDA-MB-231 | PGDB_A008125 | PGDB_C011099 | PGDB_AS001832 | View |
| Ymin | - | = | 17.2 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | PGDB_A008334 | PGDB_C011214 | PGDB_AS001848 | View |
 | EC50 | - | = | 0.008 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | PGDB_A008350 | PGDB_C011202 | PGDB_AS001798 | View |
 | EC50 | - | = | 0.108 | uM | - | — | WEE1 | - | MDA-MB-231 | PGDB_A008360 | PGDB_C011129 | PGDB_AS001832 | View |
 | EC50 | - | = | 0.585 | uM | - | — | WEE1 | - | MDA-MB-231 | PGDB_A008370 | PGDB_C011241 | PGDB_AS001832 | View |
 | EC50 | - | = | 0.003 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | PGDB_A008399 | PGDB_C011180 | PGDB_AS001798 | View |
 | Ymin | - | = | 31.5 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | PGDB_A008491 | PGDB_C011137 | PGDB_AS001848 | View |
 | Ymin | - | = | 8.7 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | PGDB_A008532 | PGDB_C011145 | PGDB_AS000997 | View |
| EC50 | - | = | 0.083 | uM | - | — | WEE1 | - | MDA-MB-231 | PGDB_A008726 | PGDB_C011178 | PGDB_AS001832 | View |