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Compound
PGDB_C011099
6 activity records1 related patents
2D structure
CN1CC[C@]2(C[C@@H](c3ccc4cc(CN5CC[C@H](Oc6ccc7c(c6)CN([C@H]6CCC(=O)NC6=O)C7=O)C5)ccc4n3)CO2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.146 | uM | - | — | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A008125 | PGDB_C011099 | PGDB_AS001832 | View |
| Ymin | - | = | 61.3 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MDA-MB-231 | WO2025137053A1 | PGDB_A012702 | PGDB_C011099 | PGDB_AS002525 | View |
| EC50 | - | = | 0.023 | uM | - | — | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A057872 | PGDB_C011099 | PGDB_AS002043 | View |
| EC50 | - | = | 0.014 | uM | - | — | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A058797 | PGDB_C011099 | PGDB_AS001798 | View |
| Ymin | - | = | 12.6 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | WO2025137053A1 | PGDB_A062484 | PGDB_C011099 | PGDB_AS000997 | View |
| Ymin | - | = | 30.9 | % | Concentration series: 1 uM, 10 uM | 4 h | WEE1 | - | 293T-LentiXWEE1-ePL | WO2025137053A1 | PGDB_A068576 | PGDB_C011099 | PGDB_AS001848 | View |