PatGlueDB | Molecular Glue Patent Bioactivity Database

Target summary

Target IDPGDB_T000096

NameNEK7

Gene symbolNEK7

Protein nameSerine/threonine-protein kinase Nek7

UniProt IDQ8TDX7

Roledegradation_target | neo_substrate | primary_target

Compounds456

Activity records1,429

Assays18

Patents5

Activity compounds and values

Activity records

1,429 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
Dmax	-	=	93	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000004	PGDB_C031206	PGDB_AS000358	View
Dmax	-	=	49	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000077	PGDB_C031279	PGDB_AS000358	View
DC50	-	=	17	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000222	PGDB_C031257	PGDB_AS000897	View
Dmax	-	=	40	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000322	PGDB_C031324	PGDB_AS000358	View
Dmax	-	=	59	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000333	PGDB_C031265	PGDB_AS000358	View
DC50	-	=	159	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000371	PGDB_C031208	PGDB_AS000897	View
Dmax	-	=	93	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000389	PGDB_C031236	PGDB_AS000358	View
DC50	-	=	79	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000405	PGDB_C031239	PGDB_AS000897	View
DC50	-	=	8	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000457	PGDB_C031273	PGDB_AS000897	View
Dmax	-	=	62	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000652	PGDB_C031306	PGDB_AS000358	View
DC50	-	=	183	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000745	PGDB_C031272	PGDB_AS000897	View
Dmax	-	=	77	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000762	PGDB_C031211	PGDB_AS000358	View
Dmax	-	=	34	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000845	PGDB_C031329	PGDB_AS000358	View
DC50	-	=	46	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000866	PGDB_C031290	PGDB_AS000897	View
DC50	-	=	50	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000876	PGDB_C031221	PGDB_AS000897	View
DC50	-	=	107	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000938	PGDB_C031280	PGDB_AS000897	View
Dmax	-	=	35	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000943	PGDB_C031305	PGDB_AS000358	View
DC50	-	=	56	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000979	PGDB_C031247	PGDB_AS000897	View
Dmax	-	=	72	%	Concentration series: 1 uM, 0.05 nM	-	NEK7	-	CAL-51	WO2026099466A1	PGDB_A000985	PGDB_C031222	PGDB_AS000358	View
DC50	-	=	112	nM	-	—	NEK7	-	CAL-51	WO2026099466A1	PGDB_A001033	PGDB_C031256	PGDB_AS000897	View

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