Activity record

PGDB_A004662

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 1.29 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000447
PatentWO2026103798A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009208
Compound IDPGDB_C009208
Compound实施例 4
Source record IDPGDB_C009208
InChIKeyWISZVTAGCRWMBJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000447
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2026103798A1
Compound location

实施例 4

实施例 4 enlarged structure实施例 4 location on patent page 67
Activity table
Page 89 · table single