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Compound
PGDB_C009208
5 activity records3 related patents
2D structure
O=C1CCN(c2cccc(-c3ccc(-n4ccccc4=O)cc3)c2Cl)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 6.72 | nM | - | — | VAV1 | - | pan-T | WO2026051943A1 | PGDB_A001909 | PGDB_C009208 | PGDB_AS000112 | View |
| IC50 | - | = | 1.29 | uM | - | — | CRBN | CRBN | - | WO2026103798A1 | PGDB_A004662 | PGDB_C009208 | PGDB_AS000447 | View |
| IC50 | - | = | 86.48 | nM | - | — | VAV1 | - | REC-1 | WO2026103798A1 | PGDB_A004899 | PGDB_C009208 | PGDB_AS000941 | View |
| Dmax | - | = | 78.314 | % | Concentration series: 10 uM, 0.5 nM | 24 h | VAV1 | - | Jurkat | WO2026013576A1 | PGDB_A020002 | PGDB_C009208 | PGDB_AS001757 | View |
| DC50 | - | = | 401.194 | nM | - | — | VAV1 | - | Jurkat | WO2026013576A1 | PGDB_A050634 | PGDB_C009208 | PGDB_AS002533 | View |